Alnylam’s (ALNY) treatment of transthyretin-mediated amyloidosis, or ATTR amyloidosis, was granted FDA orphan designation, according to a post ...

The tiny protein known as transthyretin can cause big problems in the body when it misfolds after secretion. While healthy ...

In this essay, we will explore the symptoms of ATTR-CM and the five treatment options available for the heart condition.

AstraZeneca has clearly made the rare disease transthyretin amyloidosis (ATTR) a key component of its rare disease pipeline, licensing a second drug candidate in the space of a couple of months.

Treatment modalities include liver transplantation for transthyretin-related (ATTR) amyloidosis, elimination of inflammation in amyloid A (AA) amyloidosis and intensive chemotherapy in ...

Certain features associated with ATTR-CA and AS may suggest a screening strategy going forward. People with transthyretin cardiac amyloidosis (ATTR-CA) on top of aortic stenosis (AS) fared ...

Various forms of hereditary amyloidosis have been described: transthyretin (ATTR), apolipoprotein (AApo) AI, AApoAII, gelsolin, fibrinogen Aa, cystatin C and lysozyme amyloidosis. Hereditary ...

BridgeBio could be an acquisition target, but current financial challenges and competition suggest a "Hold" rating until ...

One of the key areas of recent research is the development of new therapies for transthyretin amyloidosis (ATTR), which is a common form of amyloidosis affecting the heart. The introduction of ...

Intellia Therapeutics shifts focus to NTLA-2002 for hereditary angioedema and nex-z for ATTR amyloidosis, advancing Phase 3 trials in 2025. Strategic reorganization includes a 27% workforce ...

[18F]florbetaben has demonstrated its capability to identify amyloid deposits in the heart, including AL and ATTR. These findings led to its Orphan Drug Designation by both the European Commission ...