The following is a summary of “Histone Modifications and DNA Methylation in Psoriasis: A Cellular Perspective,” published in the January 2025 issue of Allergy and Immunology by Pan et al. Epigenetic ...

"For solid tumors—the major killers in cancer—there is a tremendous unmet need to develop new approaches to therapeutically block DNA methylation abnormalities," says corresponding co-author ...

Another way to think of the epigenome is to picture it as DNA ... 2 shows the methylation of normal skin cells (specifically, fibroblasts, which are depicted in red) and of SW48 cancer cells ...

Dysregulation of miRNA expression involved in cancer can be triggered by multiple mechanisms including aberrant DNA methylation of the miRNA gene promoter. Of note, DNA methylation of tumor ...

Ph.D. candidate in Georgetown University’s tumor biology program defended his dissertation, titled “Molecular Signatures of Treatment Responses in Tumors and Serial Liquid Biopsies in Patients with ...

Restoring these pathways by co-inhibiting DNA methylation and H3K9me2 enables ... wound healing capacity in irradiated skin from breast cancer survivors and highlight THBS1 as a key epigenetically ...

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) on December 5, 2024, Volume 16, Issue 22, titled "DNA-methylation age and ...

Professor Martin Widschwendter and his team have already shown a promising ability to predict breast and ovarian cancer long before it actually develops through spotting signature DNA methylation ...

Dunn, recently carried out a study exploring how DNA methylation, an epigenetic modification ... focused on its contribution to some types of cancer, neurological disorders and overall mental ...

Several complex diseases have aberrant DNA methylation patterns, such as different types of cancer and neurodegenerative disorders, which are often associated with genomic instability and loss of DNA ...