The standard eukaryotic cell cycle consists of four phases: G1, S, G2, and M phases. There are three phase transitions in a cell cycle: G1/S to initiate DNA synthesis, G2/M to enter mitosis ...
Cyclin-dependent kinases (CDKs) trigger the transition from G1 to S phase and from G2 to M phase by phosphorylating distinct sets of substrates. (B) CDK1 and CDK2 bind to multiple cyclins (cyclin ...