One reason behind this interaction is ibuprofen's effect on inhibiting platelet function and impairing the blood's ability to clot (per Drugs.com), meaning that their effects might add up.

ibuprofen (Advil, Motrin and generics), and naproxen (Aleve and generics). Factors that may make clots more likely include previous clotting problems, heart disease, diabetes, small blood vessels ...

The supplements could interact with blood thinners and other drugs that reduce clotting, such as aspirin and ibuprofen. They could cause excess bleeding and bruising. The FDA does regulate dietary ...

In 2017, when Isaak Sackett of Watkins was 13 years old, he experienced a blood clot in his leg and lungs after playing football and hockey. As a result, Isaak, who is now 16 and the son of Paul ...