These advancements not only deepen our knowledge of fundamental cellular mechanisms but also have implications for understanding diseases associated with NPC dysfunction. Nuclear Pore Complex (NPC ...

Nuclear pore complexes are the guardians of the human genome that is packaged into the nucleus of all cells. They form selective channels through the envelope of the nucleus and connect its interior ...

reliable general purpose monoclonal antibody which recognizes a related family of NPC proteins; believed to recognize the repeated FXFG repeat sequence in nuceloporins including p62, p152 and p90 and ...

NPC: Nuclear pore complex. Almost 50–70% of primary biliary cirrhosis (PBC) patients have antinuclear antibodies (ANA), the most relevant immunofluorescence patterns being anti-multiple nuclear ...

A known membrane-remodeling complex earns a newly identified role as a quality-assurance director during the assembly of nuclear pores. Kerry served as The Scientist’s news director until 2021. Before ...

ANA in PBC may be directed against the nuclear bodies (NB), the nuclear pore complex (NPC), centromeres, SSA/Ro, SSB/La, Scl-70, histones and other cellular nuclear constituents. [13–16] The ...