Retroviral vector-mediated gene transfer has been central to the development of gene therapy. Retroviruses have several distinct advantages over other vectors, especially when permanent gene transfer ...

Lentiviruses have the unique ability amongst retroviruses of being able to infect non-cycling ... pseudotyped with the envelope of the vesicular stomatitis virus (VSV), the vector can serve to ...

The scientists used a retroviral vector to deactivate a gene which stops a cell's life cycle and to alter the length of the telomeres on the ends of each chromosome, which improves the cells ...

Ironically, the latest technique for producing transgenic cattle is based on a retroviral vector strategy reminiscent of that employed two decades ago to produce the first genetically engineered ...

Retroviral vectors, such as those based on murine leukemia virus (MLV), have been used in gene therapy clinical trials. To address these challenges, researchers are developing novel viral vector ...

Charles River Laboratories has entered an agreement with German company Captain T Cell to focus on the production of plasmid ...

Vector production (clinical-grade plasmid DNA and retroviral vectors). Research and development work relating to vector production and transduction of patient cells. Molecular analysis of gene ...