Ubiquitin: a diverse cellular signal Ubiquitylation is among the most widely used protein modifications involved in regulating cellular signalling and homeostasis. At the molecular level ...
Damaged lysosomes are eliminated by lysophagy, yet the regulatory mechanisms of this process are not fully defined. Here, the authors identify that the TBK1-SCFFBXO3-TMEM192-TAX1BP1 axis is ...