The San Francisco 49ers, 5-5 and in last place in the NFC West, desperately need a win if they want to keep their playoff hopes alive. Now, they have an even steeper uphill climb after it was ...

LATEST Nov. 22, 2:15 p.m. The 49ers will be without both quarterback Brock Purdy (shoulder) and defensive end Nick Bosa (hip and oblique injuries) for Sunday’s game against the Packers.

SANTA CLARA — One of the most error-prone 49ers teams in recent memory has just about exhausted its margin for error. The 49ers are 5-5, having lost their third NFC ...

SANTA CLARA -- The 49ers have faced Jordan Love only once. That was last season during the playoffs. Dre Greenlaw intercepted him twice and the 49ers won. This time, Greenlaw is out. But Love is ...

The San Francisco 49ers are poised to be underdogs for the first time since 2022, breaking a chain of 36 consecutive regular-season games in which they've been favored, the third-longest such ...

SANTA CLARA — Brandon Allen prepared as if he was the 49ers’ starting quarterback all week, but the reality didn’t hit home until Friday, when Brock Purdy again missed practice.

This just isn't the 49ers' week. They have now been dealt the worst-case scenario with Nick Bosa's status against the Packers. The Week 12 injury report is an extremely demoralizing one for the ...

GREEN BAY, Wis. (AP) After losing to San Francisco in the playoffs three of the last five seasons, the Green Bay Packers wouldn’t mind seeing the 49ers get left out of the postseason entirely.

The San Francisco 49ers (5-5) head to Lambeau Field for a Week 12 showdown with the Green Bay Packers (7-3). The matchup this week is a rematch of last year’s Divisional Round. In that game, the San ...

The San Francisco 49ers announced they have signed DL Jonathan Garvin to the team's practice squad. Garvin (6-4, 257) was originally drafted by the Green Bay Packers in the seventh round (242 nd ...