Cytochrome P450 enzymes (P450s) are a diverse group of heme-containing enzymes that play a crucial role in the metabolism of various substances, including drugs and natural products. They are ...

Cytochrome P450 enzymes (CYPs) are a large family of enzymes that play a crucial role in the metabolism of various substances, including drugs and xenobiotics (foreign compounds). In cancer ...

Microbial factories provide a sustainable alternative to tree sap for producing elusive plant molecules, offering new ...

This reaction is due to the efficiency of their body's metabolism of caffeine, which primarily occurs in the liver involving ...

Their analysis uncovered a previously unknown enzyme system, referred to as P450, that is responsible ... cyclohexane through a newly discovered cytochrome enzyme system, referred to as P450PsFu.

To break down some prescription drugs in the body, the liver uses enzymes called cytochrome P450. But grapefruit juice contains chemical compounds called furanocoumarins which can block the action ...

After oral administration, pravastatin undergoes extensive first pass metabolism in the liver but metabolization is not carried out by the cytochrome P450 3A4 enzymes system to a clinically ...

A growing body of evidence links use of proton pump inhibitors to kidney problems, including kidney failure in patients with existing CKD.