Cytochrome P450 enzymes (P450s) are a diverse group of heme-containing enzymes that play a crucial role in the metabolism of various substances, including drugs and natural products. They are ...

Cytochrome P450 enzymes (CYPs) are a large family of enzymes that play a crucial role in the metabolism of various substances, including drugs and xenobiotics (foreign compounds). In cancer ...

A growing body of evidence links use of proton pump inhibitors to kidney problems, including kidney failure in patients with existing CKD.

Microbial factories provide a sustainable alternative to tree sap for producing elusive plant molecules, offering new ...

Metoprolol is used for phenotyping of cytochrome P450 (CYP) 2D6, a CYP isoform considered not to be inducible by inducers of the CYP2C, CYP2B, and CYP3A families such as rifampicin. While assessing ...

After oral administration, pravastatin undergoes extensive first pass metabolism in the liver but metabolization is not carried out by the cytochrome P450 3A4 enzymes system to a clinically ...

The same study also found that taurine reduced the resistance of blood flow in the blood vessel walls and enhanced the ...

Their analysis uncovered a previously unknown enzyme system, referred to as P450, that is responsible ... cyclohexane through a newly discovered cytochrome enzyme system, referred to as P450PsFu.

Once confined to the province of abstract theory, quantum computing seeks to use operations based on quantum mechanics to ...

State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China University of Chinese Academy of Sciences, Beijing 100049, China State Key ...

Statins and vitamin D are also metabolized (broken down) by the same liver enzyme, cytochrome P450 3A4 (CYP3A4). If you take both vitamin D and a statin, they will compete for the enzyme.

Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States Department of Chemistry, Massachusetts Institute of Technology, Cambridge, ...