A team led by UT Southwestern scientists has discovered a mechanism that promotes metastasis in pancreatic, breast, and ...

Since the application of molecular biology in cancer biology ... Notch signaling and epithelial-to-mesenchymal transition (EMT). Transformed, recruited and differentially activated cells ...

Ephrin A1 facilitates colonization and metastasis of gastric cancer cells in vitro and in vivo via inducing epithelial-mesenchymal transition (EMT). Ephrin A1 directly interacts with EGFR and induces ...

This complex interplay between oral bacteria and cancer cells offers new insights into the molecular mechanisms of OSCC, presenting novel potential targets for therapeutic intervention.

and pembrolizumab are used to treat patients with AR+ metastatic TNBC. Moreover, recent studies have shown that the aberrant activation of the EMT and Wnt/β-catenin pathway also contributes to ...

EMT in physiological and pathological conditions, examining how hybrid E/M cells contribute to tissue regeneration or drive cancer invasiveness and metastasis, with a focus on targeting these hybrid ...

Taken together, the above findings suggest that tumor stroma is far from a passive bystander during tumor metastases ... dependent junctions, epithelial–mesenchymal transition, partial ...