The San Francisco 49ers are a gigantic mess. Nothing looks right on offense. Injuries have decimated both sides of the ball.

When Kyle Shanahan became head coach of the San Francisco 49ers in 2017, the team was in the midst of a rebuilding phase.

Ever since making the switch from high school receiver to running back in college, Isaac Guerendo has had few opportunities ...

The San Francisco 49ers have struggled to get Deebo Samuel going, and one NFL analyst thinks they may not be able to.

Running back Christian McCaffrey is on injured reserve for the second time this season, but San Francisco 49ers coach Kyle ...

See who's in and who's out for the Week 14 matchup between the San Francisco 49ers and Chicago Bears on December 8, 2024.

Christian McCaffrey's injury-ridden season took another unfortunate turn when the star running back went down with another ...

The San Francisco 49ers could say goodbye to RB Jordan Mason, one of their most productive offensive players, in the near ...

San Francisco 49ers linebacker Fred Warner recently revealed that he has been playing through a bone fracture in his ankle, ...

Once their injury-plagued 2024 season is in the rearview mirror, the San Francisco 49ers will face a pivotal offseason task: ...

Josh Allen lost his top-two wide receivers from the 2023 season, but it hasn't affected the Buffalo Bills' ability to win ...

While the Chicago Bears are reeling in a six-game losing streak and having just fired their head coach, the San Francisco ...