To address these limitations of DC as immunotherapeutic agent, we have developed a polymeric nanocomplex incorporating (1) oncolytic adenovirus (oAd) co-expressing interleukin (IL)-12 and ...

The management of Leishmania donova ni (LD), responsible for fatal visceral leishmaniasis (VL), faces increasing challenges due to rising drug-unresponsiveness, leading to increasing treatment ...

Aligning therapies with the biologic clock may improve efficacy, as macrophage activity peaks early in the morning, worsening inflammatory disease symptoms.

Induces potent and long-lasting immune responses to defined antigens or whole pathogens (particles), mainly through the ...

This valuable study presents a mouse gastruloid model that can be used to generate hematopoietic progenitors as well as leukemic cells. However, in its current form, the manuscript is inadequate ...

It may be a useful approach by inhalation and an essential approach by intravenous administration, as this allows a reduction in uptake by macrophages of the liver and spleen. Therapeutic vaccines ...

Central antery hyaline degeneration of SPLEEN human pathology sample under microscope Central antery hyaline degeneration of SPLEEN human pathology sample under microscope spleen histology stock ...

Macrophages are the primary cells responsible for nanoparticle ... SaNPs are intravenously injected, accumulate in the liver, spleen and in tumor tissue, where they are passively targeted to malignant ...

Tumor-associated macrophages (TAMs) and tumor-associated neutrophils (TANs ... and can be found in peripheral blood and spleen, in addition to the tumor microenvironment. The markers used to identify ...