( MENAFN - IANS) New Delhi, Feb 4 (IANS) The global Parkinson's disease (PD) market is expected to grow to $7.9 billion by 2033 from $3.4 billion in 2023, according to a report.

The market for Parkinson’s disease (PD) drugs across the seven major geographies (7MM; USA, France, Germany, Italy, UK and ...

Epigenomic and transcriptomic analyses reveal that, during mouse spermatogenesis, the H3K79 methyltransferase ... domains and regulates PARP1/2-trapping inhibitor sensitivity via abasic site ...

A DNA methyltransferase inhibitor and all-trans retinoic acid reduce oral cavity carcinogenesis induced by the carcinogen 4-nitroquinoline 1-oxide. Triterpenoids CDDO-methyl ester or CDDO-ethyl ...

Shanghaitech University has identified thiazolidinedione compounds acting as DNA methyltransferase 3A (DNMT3A) inhibitors reported to be useful for the treatment of acute myeloid leukemia and ...

Aromatase is an enzyme that converts testosterone to estradiol, a type of estrogen. One study found that taking an estrogen blocker called an aromatase inhibitor while on testosterone therapy reduced ...

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some patients may develop resistance to DNA methylation inhibitors. In the future, in-depth research can be conducted on the molecular mechanisms related to drug resistance, such as mutations in DNA ...

National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland 20850, United States ...

This manuscript provides important structural insights into the recognition and degradation of the host tRNA methyltransferase TRMT1 by SARS-CoV-2 protease nsp5 (Mpro). The data provide compelling ...