Aug 14, 2023 · Lithium a mood stabilizer that is a used to treat or control the manic episodes of bipolar disorder (manic depression). Manic symptoms include hyperactivity, rushed speech, poor judgment, reduced need for sleep, aggression, and anger.

Lithium's actions on Gsk3 result in activation of CREB, leading to higher expression of BDNF. (Valproate, another mood stabilizer, also increases the expression of BDNF.)

Lithium is the "classic" mood stabilizer, the first to be approved by the US FDA, and still popular in treatment. Therapeutic drug monitoring is required to ensure lithium levels remain in the therapeutic range: 0.6 to 0.8 or 0.8–1.2 mEq /L (or millimolar).

Jan 14, 2024 · Lithium continues to be a first-line treatment option for mood stabilization in individuals. Pharmacists are critical in conducting medication reconciliation, assessing drug interactions, and emphasizing the significance of consistent adherence to lithium therapy to caregivers, thus improving compliance.

Jun 18, 2024 · Common mood stabilizers include lithium, anticonvulsants and antipsychotics. Lithium is a naturally occurring element and has been approved by the U.S. Food and Drug Administration (FDA) as a mood stabilizer since 1970. Brand names for lithium include: Eskalith ®. Lithobid®. Lithonate®. High levels of lithium in your blood can be dangerous.

Lithium is a mood stabilizer medication that works in the brain. It is approved for the treatment of bipolar disorder (also known as manic depression). Bipolar disorder involves episodes of depression and/or mania.

Find out how lithium treats mood disorders such as mania and bipolar disorder, and how to take it. NHS medicines information on lithium – what it's used for, side effects, dosage and who can take it.

Jan 3, 2025 · Lithium is a mood stabilizer used to treat bipolar disorder. Side effects may include diarrhea, rash, hair thinning, weight gain, and more. It can be a safe and effective treatment option when the dosage and medication schedule are followed as prescribed and precautions are taken.

Apr 24, 2023 · Although there is still more to discover about the particulars of lithium, valproic acid/divalproex, and carbamazepine, a suggested common mechanism for their mood-stabilizing abilities is inhibition of the inositol uptake process, resulting in inositol depletion.

Lithium remains a unique agent, the gold standard among the so called mood stabilizers. As Bauer and Mitchner[ 6 ] stated in their review, the evidence supports a role for lithium as a first-line agent for the treatment of manic-depressive (bipolar) disorder.