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SOLVED: Notch is an important transmembrane receptor that is present on the plasma membrane. Curiously, it possesses a proteolytic cleavage site on the intracellular portion of the protein near the predicted junction with the plasma membrane. An NLS is also present in its intracellular domain. In a protein fragment complementation experiment, the Notch receptor was fused to the N-terminal portion of GFP on its intracellular domain and transfected/expressed in cultured cells from an expression ve

SOLVED: Notch is an important transmembrane receptor that is pr…

Dr. Najeeb - Plasma Protein Plasma proteins, sometimes...

Dr. Najeeb - Plasma Protein Plasma proteins, sometimes...

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You are studying a transporter found only in the apical plasma membrane of epithelial cells. You treat the epithelial cells with a synthetic peptide that is similar to the extracellular domain of a tight junction protein. The transporter is now found in both the apical and basolateral domains of the plasma membrane. What is the most likely mechanism by which the peptide disturbs the localization of the transporter? | Numerade

You are studying a transporter found only in the apical plasma m…

SOLVED: Texts: Classify the descriptions into the correct categories to demonstrate your understanding of the three major types of membrane junctions.Gap Junction:- Does not allow material to move between cells- Contains membrane proteins called connexons between cells- Has fluid-filled pores between neighboring cells- Allows substances to pass between neighboring cellsDesmosome:- Completely attaches each cell to its neighbors- Found in the external layer of the skin (epidermis)- Provides resist

SOLVED: Texts: Classify the descriptions into the correct cate…

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