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Monocyte infiltration rather than microglia proliferation dominates the early immune response to rapid photoreceptor degeneration - Journal of Neuroinflammation
Background Activation of resident microglia accompanies every known form of neurodegeneration, but the involvement of peripheral monocytes that extravasate and rapidly transform into microglia-like macrophages within the central nervous system during degeneration is far less clear. Methods Using a combination of in vivo ocular imaging, flow ...
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